On this page How to read a codon chart
A codon is a group of three nucleotides read in the 5′ to 3′ direction. In an RNA codon chart the bases are U, C, A and G. DNA uses T in place of U. Find the first base at the left , the second base across the top , and the third base at the right . Their intersection gives the amino acid. For example, AUG encodes methionine in the standard code and is marked Start in the chart, while UUU encodes phenylalanine. Selecting a codon shows its full amino-acid name and abbreviations beside the chart, with its exact Watson–Crick anticodon pairing when an amino-acid assignment applies.
Use the search above the chart for an immediate answer: UGG shows tryptophan, Leu lists leucine’s codons, and GCN matches four alanine codons. Search accepts RNA or DNA letters.
The guided lookup follows the selected codon through the three table axes. Try ten practice questions , check your answers and explanations, or download the RNA or coding-DNA worksheet and its answer key.
Start and stop codons
AUG (ATG in DNA) is the start codon. Translation begins there with methionine, formylmethionine in bacteria. UAA, UAG and UGA (TAA, TAG and TGA in DNA) are the three stop codons, historically named ochre, amber and opal. No tRNA reads them: a release factor ends translation instead. The other 61 codons specify the 20 amino acids, so most amino acids have several codons. Leucine, serine and arginine have six each, while methionine and tryptophan have one. That redundancy does not mean every base substitution leaves the protein unchanged. Explore all nine one-base changes to a codon to see which preserve its amino-acid assignment, change it or introduce a stop.
Some organisms also start at other codons, such as GUG and UUG in bacteria (NCBI table 11 ). A start codon in a sequence is not automatically where a protein begins; the genetic-code guide explains when one is used. The bases around it matter: check a eukaryotic start codon with the Kozak sequence checker and a bacterial one with the Shine-Dalgarno sequence finder .
RNA and DNA codons
Use an RNA chart for an mRNA codon. A DNA chart gives the corresponding coding-strand triplet, with T in place of U. Both are read 5′ to 3′. Changing the alphabet does not turn a template strand into a coding strand. The DNA codon table lists all 64 in DNA letters, and the RNA menu above the chart switches the chart itself to DNA. To go from an amino acid to its codons, use the codons for each amino acid table below it. To turn a whole strand into mRNA and amino acids, use DNA to mRNA .
RNA codon
Coding DNA
Standard-code assignment
AUG
ATG
Methionine (Met, M)
UGG
TGG
Tryptophan (Trp, W)
UAA
TAA
Stop
UAG
TAG
Stop
UGA
TGA
Stop
If your input is the template strand, check the coding- and template-strand example before using a codon chart. For start signals and exceptions, read how start and stop codons are interpreted . These assignments follow NCBI table 1 ; another table can change them.
Choose the code for your sequence
The default is NCBI translation table 1, the standard code. Mitochondria and some organisms use different assignments. Open Options beside the download button (the slider icon on phones) and select another table before interpreting a sequence from one of those systems. The chart follows the NCBI genetic-code tables , including context-dependent assignments. A codon listed as a possible start is not automatically an initiation site in a real sequence.
A genetic-code chart tells you which amino acid a codon specifies. For how often a host uses each codon, compare the human, E. coli and yeast codon usage tables , with all 64 codons and downloadable counts from the named reference annotations.
Switch to the codon wheel for a center-outward view or the amino acid chart to compare names and abbreviations. To translate an entire sequence, use DNA to protein ; it lets you inspect all six reading frames.
Print or reuse your chart
The printable reference sheets are ready-made RNA and DNA versions of the standard code. Each has permanent PDF, SVG and PNG links, so you can download a one-page reference without configuring the tool or enabling JavaScript. The table and wheel show the same 64 assignments; choose the layout you find easier to follow.
For black-and-white printing , choose the RNA or DNA chart with white cells and outlined rows. All 64 codons, amino-acid abbreviations and the three base axes remain labeled; there is no color key to interpret. Each PDF fits on one A4 page. These sheets always use NCBI table 1, including when another genetic code is selected above.
In Options , Download SVG creates a vector chart that stays sharp when resized. Print uses a simplified page layout; your browser can also save that page as a PDF. SVG and PNG exports visibly label the selected RNA or DNA alphabet, full genetic-code name and NCBI table number. Code CSV saves all 64 codons of the selected table in both RNA and DNA, with internal assignments, listed initiation and stop flags, and source details. Search and display choices never shorten this file. Color groups make the chart easier to scan, while text labels keep every assignment readable without relying on color.
Inspect ambiguous codons and code differences
Type three IUPAC bases into the codon inspector to expand an ambiguous triplet. For example, GCN represents four codons that all encode alanine in the standard code. For TAN , TAA and TAG are stops while TAC and TAT encode tyrosine. The inspector lists both possible assignments instead of selecting one. The ambiguity examples in the genetic-code guide explain when a triplet can resolve. Context-dependent termination also remains unresolved.
For a nonstandard genetic code, marked codons and the differences panel identify internal assignments that differ from table 1. The panel also lists every possible initiation codon in the selected table, shows its internal amino-acid assignment, and compares the start list with table 1. Initiation markers remain separate from the count of changed internal assignments. Open Codons & context to see the selected codon's family and assignment notes. Ambiguous and context-dependent assignments open this explanation automatically. Download SVG for an editable vector reference, or PNG for a 2,400-pixel image; the amino-acid page exports its own amino-acid table.